Most of us will have heard the term 'PET Scan', even if we don't know what 'PET' stands for ('Positron Emission Tomography'), or what the scan actually entails. This video from the Helmholtz-Zentrum Dresden-Rossendorf research institute gives a good visual explanation of the process:
Basically, the patient ingests a radiotracer - a radioactive substance that is mixed with something else, such that the patient's body is 'tricked' into absorbing it as though it were a [useful] substance such as glucose. The radioactive part of the radiotracer is chosen such that (a) it emits positrons during decay and (b) it's half life - the time taken for it to decay to half its original amount - is a reasonable amount of time, e.g. an hour as opposed to 10,000 years.
Once the radiotracer is ingested, the body will transport it to the desired location (this depends on what particular radiotracer has been chosen). Positrons are then emitted in all directions into the surrounding tissue, and will annihilate with any electrons they come in contact with (this is simply what happens when matter and antimatter collide). This annihilation causes two photons (light particles) to be emitted in opposite directions. These are then detected by the PET camera on either side of the patient.
This occurs many, many times, and a cross-section image of the body is then built up, based on the position where the photons hit the camera. The camera then moves up or down the body, allowing a three-dimensional image to be created.
PET Scans highlight areas of high uptake of particular chemicals - if a glucose analogue is chosen as the radiotracer, then the resulting image will show areas of high glucose uptake, i.e. metabolism. Higher than average metabolism is one of the key signs of cancer metastasis. This is why PET Scans are considered an important tool in medical diagnosis.
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